Pharmaceuticals and Personal Care Products (PPCPs) have been frequently detected in the environment around the world. Algae play a significant role in aquatic ecosystem, thus the influence on algae may affect the life of higher trophic organisms. This review provides a state-of-the art overview of current research on the toxicity of PPCPs to algae. Nanoparticles, contained in personal care products, also have been considered as the ingredients of PPCPs. PPCPs could cause unexpected effects on algae and their communities. Chlorophyta and diatoms are more accessible and sensitive to PPCPs. Multiple algal endpoints should be considered to provide a complete evaluation on PPCPs toxicity. The toxicity of organic ingredients in PPCPs could be predicted through quantitative structure-activity relationship model, whereas the toxicity of nanoparticles could be predicted with limitations. Light irradiation can change the toxicity through affecting algae and PPCPs. pH and natural organic matter can affect the toxicity through changing the existence of PPCPs. For joint and tertiary toxicity, experiments could be conducted to reveal the toxic mechanism. For multiple compound mixture toxicity, concentration addition and independent addition models are preferred. However, there has no empirical models to study nanoparticle-contained mixture toxicity. Algae-based remediation is an emerging technology to prevent the release of PPCPs from water treatment plants. Although many individual algal species are identified for removing a few compounds from PPCPs, algal-bacterial photobioreactor is a preferable alternative, with higher chances for industrial applications.

药品和个人护理产品（PPCP）在世界范围内的环境中经常被检测到。藻类在水生生态系统中起着重要作用，因此对藻类的影响可能会影响高级营养生物的生活。这篇综述提供了有关PPCP对藻类毒性的最新研究的最新综述。个人护理产品中包含的纳米颗粒也被认为是PPCP的成分。PPCP可能会对藻类及其群落产生意想不到的影响。叶绿藻和硅藻更容易接触到PPCP，并且对PPCP敏感。应考虑多个藻类终点，以提供对PPCPs毒性的完整评估。可以通过定量构效关系模型预测PPCPs中有机成分的毒性，而纳米颗粒的毒性可以有限地预测。光照射可以通过影响藻类和PPCP来改变毒性。pH和天然有机物可通过改变PPCP的存在而影响毒性。对于联合和三次毒性，可以进行实验以揭示其毒性机理。对于多种化合物混合物的毒性，优选浓度添加和独立添加模型。但是，目前还没有经验模型来研究纳米粒子包含的混合物毒性。基于藻类的修复是防止PPCP从水处理厂释放的新兴技术。尽管已鉴定出许多个体藻类可从PPCP中去除一些化合物，但藻类细菌光生物反应器是更可取的选择，在工业应用中机会更大。