Using a novel hybrid approach integrating aspiration‐assisted bioprinting and extrusion‐based bioprinting, a zonally stratified cartilage is fabricated, in which collagen fibers are aligned with designated orientation in each zone imitating the anatomical regions and matrix orientation of native cartilage tissue. These findings, in article number 2001657 by Ibrahim T. Ozbolat and co‐workers, highlight the potential of this approach for building biologically, mechanically, and histologically relevant cartilage for tissue engineering purposes.

中文翻译：

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不含支架的生物打印：使用不含支架的组织链作为构建基块，对分层的人体关节软骨进行混合生物打印（高级医疗材料。22/2020）

使用融合了抽吸辅助生物打印和基于挤压的生物打印的新型混合方法，制造出了区域分层的软骨，其中胶原纤维在每个区域中以指定的方向对齐，从而模仿了天然软骨组织的解剖区域和基质方向。这些发现在Ibrahim T. Ozbolat及其同事的文章编号2001657中，突显了这种方法在构建生物，机械和组织学相关的软骨以进行组织工程方面的潜力。