This paper describes the measurement methods of UV cross-linked hydroxyapatite-polymers composites particularly focused on the role of their composition on structure, mechanical properties, and biocompatibility. Morphology and elemental composition were investigated with SEM-EDS. The chemical structure was analysed with FT-IR spectroscopy. Stereometric and surface roughness parameters, stress and strain in the static tensile test, and swelling kinetic of composites were also studied. Biocompatibility assessment was performed utilizing direct contact cytotoxicity assay and pro-inflammatory tests. Cell morphology observation was undertaken with confocal microscopy. The composites containing poly(vinylpyrrolidone) and gelatin revealed a 9% deformation and 164.0 ± 2.3% sorption capacity. The addition of albumin and aspartic acid results in a 16% higher deformation and 166.5 ± 3.3% equilibrium swelling. The materials were not cytotoxic. The morphology of the cells exposed to the composites remained unchanged. Composite based on poly(vinylpyrrolidone) and gelatin induced monocyte cytoplasmic extensions lengthening of 207.2% in comparison with the reference material.

本文介绍了紫外交联羟基磷灰石-聚合物复合材料的测量方法，尤其着重于其组成对结构，机械性能和生物相容性的作用。用SEM-EDS研究形态和元素组成。用FT-IR光谱分析化学结构。还研究了立体和表面粗糙度参数，静态拉伸试验中的应力和应变以及复合材料的溶胀动力学。利用直接接触细胞毒性试验和促炎试验进行生物相容性评估。共聚焦显微镜进行细胞形态观察。包含聚（乙烯基吡咯烷酮）和明胶的复合材料显示9％的形变和164.0±2.3％的吸附能力。添加白蛋白和天冬氨酸会导致变形增加16％，平衡溶胀达到166.5±3.3％。该物质无细胞毒性。暴露于复合材料的细胞的形态保持不变。与参考材料相比，基于聚乙烯吡咯烷酮和明胶的复合材料诱导的单核细胞胞质延伸延长了207.2％。