Solid electrolyte interphase (SEI) has been widely recognized as the most important and the least understood component in lithium batteries. Considering the intrinsic instability in both chemical and mechanical, the failure of SEI is inevitable and strongly associated with the performance decay of practical working batteries. In this Review, the failure mechanisms and the corresponding regulation strategies of SEI are focused. Firstly, the fundamental properties of SEI, including the formation principles, and the typical composition and structures are briefly introduced. Moreover, the common SEI failure modes involving thermal failure, chemical failure, and mechanical failure are classified and discussed, respectively. Beyond that, the regulation strategies of SEI with respect to different failure modes are further concluded. Finally, the future endeavor in further disclosing the mysteries of SEI is prospected.

固态电解质中间相（SEI）已被广泛认为是锂电池中最重要和了解最少的组件。考虑到化学和机械的固有不稳定性，SEI的故障是不可避免的，并且与实际工作电池的性能下降密切相关。在这篇综述中，着重介绍了SEI的失效机理和相应的调节策略。首先，简要介绍了SEI的基本性质，包括形成原理，典型的组成和结构。此外，分别对涉及热故障，化学故障和机械故障的常见SEI故障模式进行了分类和讨论。除此之外，进一步总结了SEI针对不同失效模式的调节策略。最后，