Background/Objective: The aim was to evaluate the evolution of depressive symptoms and to explore the influence of physical activity (PA) practice during the home confinement due to the COVID-19 outbreak in Spain. Method: Information was collected from 595 confined participants who reported personal and contextual information, depressive symptoms and PA levels at four time points. Results: The changes in depressive symptoms were analyzed using a linear mixed model with cubic splines. Results showed a significant increase, with a significant rise between T1 and T2 (OR = 2.38, 95% CI = 1.83-3.10). It continued growing until T4 (OR = 2.93, 95% CI = 1.97-4.38). A negative relationship was observed between the increase in depressive symptoms and moderate-to-vigorous physical activity (MVPA) levels, with a significant slope up to 4 hours of MVPA per week (OR = 0.51, 95% CI = 0.29-0.90) that tended to increase until 16 hours per week of MVPA (OR = 0.41, 95% CI = 0.20-0.87). Conclusions: Results from a partition model showed that moderate intensity of PA could be enough to prevent an increase of depressive symptoms during home isolation.

背景/目的：目的是评估抑郁症状的演变，并探讨由于西班牙 COVID-19 爆发而在家中进行体力活动 (PA) 练习的影响。方法：从 595 名受限参与者那里收集信息，他们在四个时间点报告了个人和背景信息、抑郁症状和 PA 水平。结果：使用三次样条线性混合模型分析抑郁症状的变化。结果显示显着增加，T1 和 T2 之间显着增加（OR = 2.38，95% CI = 1.83-3.10）。它持续生长直至 T4（OR = 2.93，95% CI = 1.97-4.38）。抑郁症状的增加与中度至剧烈体力活动 (MVPA) 水平之间存在负相关关系，每周进行 4 小时的 MVPA 时呈显着斜率（OR = 0.51，95% CI = 0.29-0.90），表明每周 MVPA 持续 16 小时之前，该比例呈增加趋势（OR = 0.41，95% CI = 0.20-0.87）。结论：分区模型的结果表明，中等强度的 PA 足以防止家庭隔离期间抑郁症状的增加。