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Current knowledge and perspectives of potential impacts of Salmonella enterica on the profile of the gut microbiota
BMC Microbiology ( IF 4.0 ) Pub Date : 2020-11-17 , DOI: 10.1186/s12866-020-02008-x
Nesreen H Aljahdali 1, 2 , Yasser M Sanad 1, 3, 4 , Jing Han 1 , Steven L Foley 1
Affiliation  

In the past decade, the initial studies of the gut microbiota started focusing on the correlation of the composition of the gut microbiota and the health or diseases of the host, and there are extensive literature reviews pertaining to this theme. However, little is known about the association between the microbiota, the host, and pathogenic bacteria, such as Salmonella enterica, which is among the most important foodborne pathogens and identified as the source of multiple outbreaks linked to contaminated foods causing salmonellosis. Secretion systems, flagella, fimbriae, endotoxins, and exotoxins are factors that play the most important roles in the successful infection of the host cell by Salmonella. Infections with S. enterica, which is a threat to human health, can alter the genomic, taxonomic, and functional traits of the gut microbiota. The purpose of this review is to outline the state of knowledge on the impacts of S. enterica on the intestinal microbiota and highlight the need to identify the gut bacteria that could contribute to salmonellosis.

中文翻译:

目前关于沙门氏菌对肠道微生物群的潜在影响的知识和观点

在过去的十年中,肠道微生物群的初步研究开始关注肠道微生物群的组成与宿主的健康或疾病之间的相关性,并且有大量与该主题相关的文献综述。然而,人们对微生物群、宿主和致病细菌(例如肠道沙门氏菌)之间的关联知之甚少,沙门氏菌是最重要的食源性病原体之一,被确定为与导致沙门氏菌病的受污染食品相关的多次爆发的源头。分泌系统、鞭毛、菌毛、内毒素和外毒素是沙门氏菌成功感染宿主细胞的最重要因素。感染 S. enterica 对人类健康构成威胁,可以改变肠道微生物群的基因组、分类和功能特征。
更新日期:2020-11-17
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