Future directions in preclinical and translational cancer neuroscience research,Nature Cancer

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Future directions in preclinical and translational cancer neuroscience research
Nature Cancer ( IF 23.5 ) Pub Date : 2020-11-17 , DOI: 10.1038/s43018-020-00146-9
Ihsan Ekin Demir _{1,

2,

3,

4} , Carmen Mota Reyes _{1,

3,

4} , Wasfi Alrawashdeh ₅ , Güralp O Ceyhan ₂ , Sylvie Deborde ₆ , Helmut Friess _{1,

3,

4} , Kıvanç Görgülü ₇ , Rouzanna Istvanffy _{1,

3,

4} , David Jungwirth _{1,

3,

4} , Rohini Kuner ₈ , Maria Maryanovich _{9,

10} , Shorook Na'ara _{11,

12} , Simon Renders _{13,

14} , Jami L Saloman ₁₅ , Nicole N Scheff ₁₆ , Hendrik Steenfadt _{1,

3,

4} , Pavel Stupakov _{1,

3,

4} , Vera Thiel _{13,

14} , Divij Verma _{9,

10} , Bengi Su Yilmaz _{1,

3,

4} , Ruth A White ₁₇ , Timothy C Wang ₁₈ , Richard J Wong ₆ , Paul S Frenette _{9,

10,

19} , Ziv Gil _{11,

12} , , Brian M Davis ₂₀

Affiliation

Department of Surgery, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.
Department of General Surgery, HPB-Unit, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
German Cancer Consortium, Partner Site Munich, Munich, Germany.
CRC 1321 Modeling and Targeting Pancreatic Cancer, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.
Department of HPB and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, UK.
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Comprehensive Cancer Center Munich, Klinikum rechts der Isar, Technical University of Munich, School of Medicine, Munich, Germany.
Department of Molecular Pharmacology, Institute of Pharmacology, Heidelberg University, Heidelberg, Germany.
Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY, USA.
Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Department of Otolaryngology, Head and Neck Surgery, and the Laboratory for Applied Cancer Research, Rappaport Institute of Medicine and Research, The Technion, Israel Institute of Technology, Haifa, Israel.
Head and Neck Center, Rambam Healthcare Campus, Haifa, Israel.
Division of Stem Cells and Cancer, German Cancer Research Center and DKFZ-ZMBH Alliance, Heidelberg, Germany.
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Department of Medicine, Division of Gastroenterology, Hepatology, & Nutrition, Center for Neuroscience at the University of Pittsburgh, Pittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Hillman Cancer Center and Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Division of Hematology and Oncology, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, NY, USA.
Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, NY, USA.
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Center for Neuroscience at the University of Pittsburgh, Pittsburgh Center for Pain Research and Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Recent advances in cancer neuroscience necessitate the systematic analysis of neural influences in cancer as potential therapeutic targets in oncology. Here we outline recommendations for future preclinical and translational research in this field.

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