Identification of the Aedes aegypti nAChR gene family and molecular target of spinosad,Pest Management Science

当前位置： X-MOL 学术 › Pest Manag. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Identification of the Aedes aegypti nAChR gene family and molecular target of spinosad
Pest Management Science ( IF 3.8 ) Pub Date : 2020-11-17 , DOI: 10.1002/ps.6183
Jianqiang Lan ₁ , Zihe Wang ₁ , Zhaohui Chen ₁ , Lei Zhang ₁ , Jianguo Zhao ₁ , Qingfeng Guan ₁ , Chenghong Liao ₁ , Nannan Liu ₂ , Qian Han ₁

Affiliation

Spinosad is an insecticide with unique mode of action (MOA) of disrupting nicotinic acetylcholine receptor and is efficacious against many insect species. Mutations in the nicotinic acetylcholine receptor (nAChR) α6 subunit have been identified that are associated with levels of spinosad resistance, but the molecular characterization of the nAChR gene family and a causative association between nAChR α6 and resistance to spinosad in Aedes aegypti, a primary vector of many arboviruses, have not yet been reported.

中文翻译：

埃及伊蚊nAChR基因家族的鉴定和多杀菌素的分子靶标

Spinosad是一种具有独特作用模式（MOA）的杀虫剂，可破坏烟碱乙酰胆碱受体，对多种昆虫均有效。已鉴定出烟碱型乙酰胆碱受体（nAChR）α6亚基的突变与多杀菌素抗性水平相关，但nAChR基因家族的分子特征以及nAChRα6与埃及伊蚊对多杀菌素的抗性之间有因果关系，这是主要载体许多虫媒病毒尚未被报道。

更新日期：2020-11-17

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11