A putative novel clade within the genus Streptomyces was discovered following antifungal screening against Pseudogymnoascus destructans, the causative agent of white-nose syndrome, and described using multi-locus sequencing analysis. Swabs from both the cave myotis bat (Myotis velifer) and the Brazilian free-tailed bat (Tadarida brasiliensis) in southern New Mexico bore isolates AC536, AC541^T and AC563, which were characterised using phylogenetic, morphological, and phenotypic analyses. Multi-locus sequence analysis positions AC541^T with neighbors Streptomyces rubidus (NRRL B-24619^T), Streptomyces guanduensis (NRRL B-24617^T), and Streptomyces yeochonensis (NRRL B-24245^T). A complete genome of the type strain was assembled to determine its taxonomy and secondary metabolite potential. ANI comparisons between all closely related types strains are shown to be well below the 95–96% species delineation. DNA-DNA relatedness between AC541^T and its nearest neighbors ranged between 23.7 and 24.1% confirming novelty. Approximately 1.49 Mb or 17.76% of the whole genome is devoted to natural product biosynthesis. The DNA G + C content of the genomic DNA of the type strain is 73.13 mol %. Micromorphology depicts ovoid spores with smooth surfaces in flexuous chains. Strains presented an ivory to yellow hue on most ISP media except inorganic salts-starch agar (ISP4) and can grow on d-glucose, mannitol, and d-fructose, but exhibited little to no growth on l-arabinose, sucrose, d-xylose, inositol, l-rhamnose, d-raffinose, and cellulose. This clade possesses the capability to grow from 10 to 45 °C and 12.5% (w/v) NaCl. There was strain growth variation in pH, but all isolates thrive at alkaline levels. Based on our polyphasic study of AC541^T, the strain warrants the assignment to a novel species, for which the name Streptomyces buecherae sp. nov. is proposed. The type strain is AC541^T (= JCM 34263^T, = ATCC TSD201^T).

链霉菌属内的一个推定的新进化枝是在针对白鼻综合征的病原体Pseudogymnoascus destructans 进行抗真菌筛选后发现的，并使用多位点测序分析进行描述。来自新墨西哥州南部的洞穴肌蝠 ( Myotis velifer ) 和巴西无尾蝙蝠 ( Tadarida brasiliensis ) 的拭子分离出 AC536、AC541 ^T和 AC563，使用系统发育、形态学和表型分析对其进行了表征。多位点序列分析定位 AC541 ^T与邻居Streptomyces rubidus (NRRL B-24619 ^T ), Streptomyces guanduensis(NRRL B-24617 ^T ) 和Streptomyces yeochonensis (NRRL B-24245 ^T )。组装了该类型菌株的完整基因组以确定其分类学和次生代谢物潜力。所有密切相关类型菌株之间的 ANI 比较显示远低于 95-96% 的物种划分。AC541 ^T之间的 DNA-DNA 相关性其最近的邻居在 23.7% 到 24.1% 之间，证实了新颖性。大约 1.49 Mb 或整个基因组的 17.76% 用于天然产物生物合成。该类型菌株基因组DNA的DNA G+C含量为73.13 mol%。微形态学描绘了在弯曲链中具有光滑表面的卵形孢子。菌株呈现的象牙到黄色色调上最ISP介质除无机盐-淀粉琼脂（ISP4），并且可以上生长d葡萄糖，甘露糖醇，和d -fructose，但展出几乎没有生长上升-arabinose，蔗糖，d -木糖、肌醇、l-鼠李糖、d-棉子糖和纤维素。该进化枝具有在 10 到 45 °C 和 12.5% (w/v) NaCl 的条件下生长的能力。pH 值存在菌株生长变化，但所有分离株都在碱性水平下茁壮成长。根据我们对 AC541 ^{T 的}多相研究，该菌株有理由分配给一个新物种，其名称为Streptomyces buecherae sp。十一月 被提议。类型菌株是 AC541 ^T (= JCM 34263 ^T , = ATCC TSD201 ^T )。