In nowadays, we have entered the new era of pandemics and the significance of virus detection deeply impacts human society. Viruses with genetic mutations are reported nearly every year, and people have prepared tools to detect the virus and vaccines to ensure proper treatments. Influenza virus (IV) is one of the most harmful viruses reporting various mutations, sub-types, and rapid infection speed for humans and animals including swine and poultry. Moreover, IV infection presents several harmful symptoms including cough, fever, diarrhea, chills, even causing death. To reduce the IV-induced harm, its proper and rapid detection is highly required. Conventional techniques were used against various IV sub-types including H1N1, H3N2, and H5N1. However, some of the techniques are time-consuming, expensive, or labor-intensive for detecting IV. Recently, the nucleic acid-based aptamer has gained attention as a novel bioprobe for constructing a biosensor. In this review, the authors discuss the recent progress in aptasensors for detecting IV in terms of an electrochemical and an optical biosensor.

当今，我们进入了流行病的新时代，病毒检测的意义深刻地影响着人类社会。几乎每年都会报告带有基因突变的病毒，人们已经准备好检测病毒的工具和疫苗，以确保适当的治疗。流感病毒 (IV) 是对人类和动物（包括猪和家禽）报告各种突变、亚型和快速感染速度的最有害病毒之一。此外，IV感染会出现多种有害症状，包括咳嗽、发烧、腹泻、寒战，甚至导致死亡。为了减少静脉注射引起的伤害，非常需要对其进行正确和快速的检测。常规技术用于对抗各种 IV 亚型，包括 H1N1、H3N2 和 H5N1。然而，一些技术用于检测 IV 是耗时、昂贵或劳动密集型的。最近，基于核酸的适体作为一种用于构建生物传感器的新型生物探针而受到关注。在这篇综述中，作者讨论了在电化学和光学生物传感器方面检测 IV 的适体传感器的最新进展。