Recent advances in dioxaborine-based fluorescent materials for bioimaging applications,Materials Horizons

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Recent advances in dioxaborine-based fluorescent materials for bioimaging applications
Materials Horizons ( IF 12.2 ) Pub Date : 2020-10-27 , DOI: 10.1039/d0mh01186j
Mayeul Collot ₁

Affiliation

Fluorescent materials are continuously contributing to important advances in the field of bioimaging. Among these materials, dioxaborine-based fluorescent materials (DBFM) are arousing growing interest. Due to their rigid structures conferred by a cyclic boron complex, DBFM possess appealing photophysical properties including high extinction coefficients and quantum yields as well as emission in the near infrared, enhanced photostability and high two-photon absorption. We herein discuss the recent advances of DBFM that found use in bioimaging applications. This review covers the development of fluorescent molecular probes for biomolecules (DNA, proteins), small molecules (cysteine, H₂O₂, oxygen), ions and the environment (polarity, viscosity) as well as polymers and nanomaterials used in bioimaging. This review aims at providing a comprehensive and critical insight on DBFM by highlighting the assets of these promising materials in bioimaging but also by pointing out their limitations that would require further developments.

中文翻译：

用于生物成像应用的基于二氧硼化物的荧光材料的最新进展

荧光材料不断为生物成像领域的重要进步做出贡献。在这些材料中，基于二氧硼化物的荧光材料（DBFM）引起了越来越多的关注。由于其由环状硼络合物赋予的刚性结构，DBFM 具有吸引人的光物理性质，包括高消光系数和量子产率以及近红外发射、增强的光稳定性和高双光子吸收。我们在此讨论了在生物成像应用中发现的 DBFM 的最新进展。这篇综述涵盖了用于生物分子（DNA、蛋白质）、小分子（半胱氨酸、H ₂ O ₂、氧）、离子和环境（极性、粘度）以及用于生物成像的聚合物和纳米材料。本综述旨在通过强调这些有前途的材料在生物成像中的资产，同时指出它们需要进一步发展的局限性，从而对 DBFM 提供全面和批判性的见解。

更新日期：2020-11-27

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