ABSTRACT

This study aimed to control the degradation of Mg–Zn–Ca alloy and improve its biocompatibility using a biodegradable Zn-modified calcium phosphate coating via dual-pulse electrodeposition. The formation mode and process of the coating were studied herein. Scanning electron microscopy revealed that the coating particles were compactly and neatly packed, and X-ray diffraction analysis, transmission electron microscopy, Fourier transform infrared spectrophotometer and X-ray photoelectron spectroscopy revealed that the coating comprises CaZn₂(PO₄)₂•2H₂O. The introduction of Zn changes the formation mechanism of coating. The degradation behaviour of the coated Mg alloy was investigated via immersion test and electrochemical test in simulated body fluid. The results show that this non-stoichiometric Zn-modified calcium phosphate coating is biodegradable and has a better protective effect. In addition, the Zn-containing coating has hydrophilic property which is beneficial to enhance the cellular response to the implant’s surface and increase apatite formation rate.

摘要

这项研究旨在通过双脉冲电沉积使用可生物降解的锌改性磷酸钙涂层来控制Mg-Zn-Ca合金的降解并提高其生物相容性。本文研究了涂层的形成方式和过程。扫描电子显微镜显示涂层颗粒紧密整齐，X射线衍射分析，透射电子显微镜，傅立叶变换红外分光光度计和X射线光电子能谱显示涂层包含CaZn ₂（PO ₄）₂ •2H _2。O.锌的引入改变了涂层的形成机理。通过浸入试验和电化学试验在模拟体液中研究了涂层镁合金的降解行为。结果表明，这种非化学计量的锌改性磷酸钙涂层是可生物降解的，并具有更好的保护作用。另外，含锌涂层具有亲水性，这有利于增强对植入物表面的细胞反应并增加磷灰石的形成速率。