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Long reach of the NAAG family tree
Journal of Neurochemistry ( IF 4.2 ) Pub Date : 2020-11-16 , DOI: 10.1111/jnc.15213
Steve Williams 1 , Caroline D. Rae 2
Affiliation  

The last common ancestor of humans and fruit flies lived about 800 million years ago, yet both of us have nervous systems that share a number of common important features, for example the use of glutamate as a neurotransmitter. We can now possibly add another common feature to the neural tissue of humans and fruit flies which is that of N‐acetylaspartylglutamate (NAAG) peptides. This Editorial highlights an article by Kozik and coworkers in the current issue of the Journal of Neurochemistry, in which the authors report the discovery, in Drosophila melanogaster nervous system, of NAA‐glutamylglutamate (NAAG2).

中文翻译:

NAAG家谱的影响范围很广

人类和果蝇的最后一个祖先大约生活在8亿年前,但是我们两个人的神经系统都有许多共同的重要特征,例如使用谷氨酸作为神经递质。现在,我们可以向人和果蝇的神经组织添加另一个共同特征,即N-乙酰基天冬氨酰胺(NAAG)肽。这篇社论重点介绍了Kozik及其同事在最新一期《神经化学杂志》上发表的一篇文章,其中作者报道了在果蝇黑腹神经系统中发现了NAA-谷氨酰谷氨酸(NAAG2)。
更新日期:2021-01-20
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