Abstract In the present study, the capture efficiency (CE) of nanoparticles flowing in a stenosed vessel was modeled computationally. The effect of parameters including the degree of constriction, constriction length, transversal location of constriction, location of current-carrying wire, and two consecutive occlusions in a cylindrical vessel with localized occlusion under the influence of magnetic field was investigated. The simulation results unveiled the substantial effect of the occluded vessel on the CE. The CE was enhanced from 21% to 24.1% by increasing the longitudinal distance of current-carrying wire from 2.5D to 5.5D. Besides, an increase in the degree of constriction from 0 to 65% resulted in a reduction in CE from 23.9% to 21%, respectively. Moreover, it was found that the change in the transversal location of constriction, and the presence of the consecutive occlusion, have a significant effect on the capturing particles in the tumor's location.

中文翻译：

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几何参数对狭窄血管中磁场影响下纳米颗粒捕获效率的影响

摘要 在本研究中，纳米粒子在狭窄血管中流动的捕获效率 (CE) 被计算建模。研究了在磁场影响下，在具有局部闭塞的圆柱形血管中，包括收缩程度、收缩长度、收缩横向位置、载流线位置以及连续两次闭塞等参数的影响。模拟结果揭示了闭塞血管对 CE 的实质性影响。通过将载流线的纵向距离从 2.5D 增加到 5.5D，CE 从 21% 提高到 24.1%。此外，收缩程度从 0 增加到 65% 导致 CE 分别从 23.9% 减少到 21%。此外，发现收缩的横向位置的变化，