Abstract Multiwall carbon nanotubes incorporated with iron oxide nanoparticles (MWCNTs-iron oxide) were prepared using a cheap, facile in-situ flame synthesis method. The nanocomposites were characterized using scanning electron microscopy, energy-dispersive X-ray spectroscopy, transmission electron microscopy, X-ray powder diffractometry, and Raman spectroscopy. MWCNTs-iron oxide nanocomposite was used to fabricate a sensitive electrochemical sensor for the detection and quantification of proguanil. The fabrication of the sensor was done by modifying a glassy carbon electrode with multiwall carbon nanotubes-iron oxide nanocomposite (MWCNTs-iron oxide). Differential pulse voltammetry (DPV) and cyclic voltammetry (CV) were used to study the electrochemical oxidation of proguanil. The selectivity of the sensor was investigated in the presence of organic and inorganic interfering agents. Furthermore, spiked human urine samples and pharmaceutical formulation were used to evaluate the utility of the sensor. A detection limit of 1.96 × 10−8 M was obtained under optimum conditions. MWCNTs-iron oxide nanocomposite can, therefore, be used to fabricate electrochemical sensors for quality control purposes.

中文翻译：

---

纳米复合材料 (MWCNTs-Fe2O3) 的简单原位火焰合成，用于药物制剂中氯胍的电化学传感

摘要 使用廉价、简便的原位火焰合成方法制备了掺入氧化铁纳米颗粒 (MWCNTs-氧化铁) 的多壁碳纳米管。使用扫描电子显微镜、能量色散 X 射线光谱、透射电子显微镜、X 射线粉末衍射和拉曼光谱对纳米复合材料进行表征。MWCNTs-氧化铁纳米复合材料用于制造灵敏的电化学传感器，用于检测和定量氯胍。传感器的制造是通过用多壁碳纳米管-氧化铁纳米复合材料（MWCNTs-氧化铁）修饰玻璃碳电极来完成的。差分脉冲伏安法（DPV）和循环伏安法（CV）被用来研究氯胍的电化学氧化。在有机和无机干扰剂的存在下研究了传感器的选择性。此外，使用加标人尿样品和药物制剂来评估传感器的效用。在最佳条件下获得了 1.96 × 10-8 M 的检测限。因此，MWCNTs-氧化铁纳米复合材料可用于制造用于质量控制目的的电化学传感器。