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Scandium Triflate Catalyzed Nazarov Cyclization of Arylvinyl Epoxides Derived from Alkoxides and Chloro(aryl)carbenes: A Facile Access to Resveratrol-Derived Natural Products
Synlett ( IF 2 ) Pub Date : 2020-11-13 , DOI: 10.1055/s-0040-1705974
Gangarajula Sudhakar 1, 2 , Nagam Satish 1, 2
Affiliation  

The reaction of arylvinyl alkoxides with chloro(aryl)carbenes provided the corresponding arylvinyl epoxides that underwent Nazarov cyclization in a catalytic amount of scandium triflate, providing easy access to several highly substituted indenes, including some resveratrol-derived natural products.



中文翻译:

三氟甲磺酸催化衍生自醇盐和氯(芳基)卡宾的芳基乙烯基环氧化合物的纳扎罗夫环化反应:便捷地获得白藜芦醇衍生的天然产物

芳基乙烯基醇盐与氯(芳基)卡宾的反应提供了相应的芳基乙烯基环氧化物,它们在催化量的三氟甲磺酸scan中经历了纳扎罗夫环化,可轻松获得数个高度取代的茚基,包括一些白藜芦醇衍生的天然产物。

更新日期:2020-11-15
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