Biofilms are increasingly implicated as playing a major role in waterborne cryptosporidiosis. This review aims to synthesize all currently available data on interactions between Cryptosporidium oocysts and biofilms. Initially described following a waterborne outbreak, the integration of Cryptosporidium oocysts in biofilm has been well demonstrated. Biofilms appear important in the dissemination/protection of oocysts in the environment. Consequently, it has been suggested that substrate-associated biofilms should be systematically considered in oocyst water quality assessment. The influence of physicochemical parameters has been studied on oocyst biofilm retention. Biofilm surface roughness, ionic concentration (especially Ca²⁺), laminar/turbulent flow, shear stress, and electrostatic repulsion forces appear important to consider regarding oocyst release from biofilm. However, data analysis carried out during this review also revealed important gaps in biological interactions within biofilms, offering many perspectives for future work.

中文翻译：

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隐孢子虫-生物膜相互作用：审查。

生物膜在水生隐孢子虫病中起着重要作用。这篇综述旨在综合有关隐孢子虫卵囊和生物膜之间相互作用的所有当前可用数据。最初描述于水源性暴发之后，隐孢子虫卵囊在生物膜中的整合已得到充分证明。生物膜在环境中卵囊的传播/保护中似乎很重要。因此，建议在卵囊水质评估中应系统地考虑与基质相关的生物膜。已研究了理化参数对卵囊生物膜保留的影响。生物膜表面粗糙度，离子浓度（尤其是Ca ²⁺），对于从生物膜释放卵囊，层流/湍流，剪切应力和静电排斥力似乎很重要。但是，本次审查期间进行的数据分析也揭示了生物膜内生物相互作用的重要缺口，为今后的工作提供了许多前景。