Cancer is one of the leading causes of annual deaths worldwide, accounting for nearly 10 million deaths each year. Metastasis, the process by which cancer spreads across the patient's body, is the main cause of death in cancer patients. Because the rising trend observed in statistics of new cancer cases and cancer‐related deaths does not allow for an optimistic viewpoint on the future—in relation to this terrible disease—the scientific community has sought methods to enable early detection of cancer and prevent the apparition of metastatic tumors. One such method is known as liquid biopsy, wherein a sample is taken from a bodily fluid and analyzed for the presence of CTCs or other cancer biomarkers (e.g., growth factors). With this objective, interest is growing by year in electrokinetically‐driven microfluidics applied for the concentration, capture, filtration, transportation, and characterization of CTCs. Electrokinetic techniques—electrophoresis, dielectrophoresis, electrorotation, and electrothermal and EOF—have great potential for miniaturization and integration with electronic instrumentation for the development of point‐of‐care devices, which can become a tool for early cancer diagnostics and for the design of personalized therapeutics. In this contribution, we review the state of the art of electrokinetically‐driven microfluidics for cancer cells manipulation.

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用于癌细胞操作的电动驱动微流体的调查

癌症是全球每年死亡的主要原因之一，每年造成近 1000 万人死亡。转移，即癌症在患者全身扩散的过程，是癌症患者死亡的主要原因。由于在新癌症病例和癌症相关死亡的统计数据中观察到的上升趋势不允许对未来（与这种可怕的疾病有关）抱有乐观的看法，因此科学界已经寻求方法来及早发现癌症并防止幻影出现转移性肿瘤。一种这样的方法被称为液体活检，其中从体液中取出样本并分析 CTC 或其他癌症生物标志物（例如，生长因子）的存在。为了这个目标，人们对应用于浓缩的电动驱动微流体的兴趣逐年增长，CTC 的捕获、过滤、运输和表征。电动技术——电泳、介电泳、电旋转、电热和 EOF——在小型化和与电子仪器集成以开发即时护理设备方面具有巨大潜力，可以成为早期癌症诊断和个性化设计的工具疗法。在这篇文章中，我们回顾了用于癌细胞操作的电动驱动微流体技术的最新进展。它可以成为早期癌症诊断和个性化治疗设计的工具。在这篇文章中，我们回顾了用于癌细胞操作的电动驱动微流体技术的最新进展。它可以成为早期癌症诊断和个性化治疗设计的工具。在这篇文章中，我们回顾了用于癌细胞操作的电动驱动微流体技术的最新进展。