Epilepsy with myoclonic‐atonic seizures (EMAS) is a rare childhood onset epileptic encephalopathy. There is no clear consensus for recommended treatments, and pharmacoresistance is common. To better assess the clinical phenotype, most effective treatment, and determinants of cognitive and seizure outcomes, three major pediatric epilepsy centers combined data, creating the largest cohort of patients with EMAS ever studied to date.

中文翻译：

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癫痫伴肌阵挛-张力性癫痫（Doose 综合征）：通过大型回顾性多中心队列阐明诊断和治疗方案

癫痫伴肌阵挛-张力性癫痫发作 (EMAS) 是一种罕见的儿童期癫痫性脑病。对于推荐的治疗方法没有明确的共识，药物耐药性很常见。为了更好地评估临床表型、最有效的治疗以及认知和癫痫结果的决定因素，三个主要的儿科癫痫中心结合了数据，创建了迄今为止研究过的最大的 EMAS 患者队列。