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Diagnostic approaches for the rapid detection of Zika virus-A review
Process Biochemistry ( IF 3.7 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.procbio.2020.11.009
Md. Anish Alam , Mohd. Rahil Hasan , Nigar Anzar , Shariq Suleman , Jagriti Narang

Abstract Mosquito-borne flavivirus is associated with the zika virus (ZIKV) which is the attention of numerous public health hazards & enduring epidemic for many years and was first identified in 1947. Formerly partial to sporadic cases in Asia & Africa but in Brazil, the zika virus appearance in 2015 indicated fast spreading all over Americans. It has been acknowledged as a global public health emergency by the World Health Organization (WHO) in 2016. Symptoms normally appear as mild-influenza, neurological signs, and subclinical manifestations with the syndrome of microcephaly in offspring that are born from infected mothers & Guillain-Barre syndrome (GBS) in adults. There is no cure or effective Zika Virus treatment known to date. Easy and efficient detection of the zika virus can reduce the risk of sickness and the successful management of this disease. Conventional techniques currently available are focused on clinical manifestation, along with molecular and serological detection tools that can identify the zika virus but due to their various disadvantages such as low specificity and sensitivity, there is a need for a quick and easy approach for the diagnosis of zika virus. Scientists are showing great interest in an effective portable and simple detection method to diagnose the Zika virus. Biosensor is considered a viable advanced system that can meet all the aforementioned demands. Biosensors are combined with an effortless approach to allow them for exploiting in various applications. This review summarizes the diagnosis, surveillance, and advancement in sensing technology for easy and successful detection of Zika virus and its usage as a fast and rapid analytical tool.

中文翻译:

快速检测寨卡病毒的诊断方法-A 综述

摘要 蚊媒黄病毒与寨卡病毒(ZIKV)有关,该病毒多年来一直受到众多公共卫生危害和持续流行,于 1947 年首次被发现。 2015 年寨卡病毒的出现表明在美国人中迅速传播。2016 年,世界卫生组织 (WHO) 将其确认为全球突发公共卫生事件。 症状通常表现为轻度流感、神经系统体征和亚临床表现,由受感染的母亲和格林兰所生的后代出现小头畸形综合征- 成人巴雷综合征 (GBS)。迄今为止,尚无治愈方法或有效的寨卡病毒治疗方法。轻松有效地检测寨卡病毒可以降低患病风险和成功管理这种疾病。目前可用的常规技术侧重于临床表现,以及可以识别寨卡病毒的分子和血清学检测工具,但由于其特异性和敏感性低等各种缺点,需要一种快速简便的方法来诊断寨卡病毒寨卡病毒。科学家们对一种有效的便携式简单检测方法来诊断寨卡病毒表现出极大的兴趣。生物传感器被认为是一种可行的先进系统,可以满足上述所有需求。生物传感器与一种轻松的方法相结合,使它们能够在各种应用中加以利用。本综述总结了诊断、监测、
更新日期:2021-02-01
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