Biomaterials Advances ( IF 5.5 ) Pub Date : 2020-11-14 , DOI: 10.1016/j.msec.2020.111733 Mariana Calin , Jithin Vishnu , Pramote Thirathipviwat , Monica-Mihaela Popa , Maria Krautz , Geetha Manivasagam , Annett Gebert
Present work unveils novel magnetic resonance imaging (MRI) compatible glassy Ti-Zr-Nb-Hf-Si alloys designed based on a high entropy alloys approach, by exploring the central region of multi-component alloy phase space. Phase analysis has revealed the amorphous structure of developed alloys, with a higher thermal stability than the conventional metallic glasses. The alloys exhibit excellent corrosion properties in simulated body fluid. Most importantly, the weak paramagnetic nature (ultralow magnetic susceptibility) and superior radiopacity (high X-ray attenuation coefficients) offer compatibility with medical diagnostic imaging systems thereby opening unexplored realms for biomedical applications.
中文翻译:
基于高熵合金设计可生物相容的Ti-Zr-Nb-Hf-Si金属玻璃
本工作通过探索多组分合金相空间的中心区域,揭示了一种新型的兼容磁共振成像(MRI)的玻璃态Ti-Zr-Nb-Hf-Si合金,该合金是基于高熵合金方法设计的。相分析表明,已开发合金的非晶态结构具有比常规金属玻璃更高的热稳定性。该合金在模拟体液中显示出优异的腐蚀性能。最重要的是,弱顺磁特性(超低磁化率)和出色的射线不透性(高X射线衰减系数)与医学诊断成像系统兼容,从而为生物医学应用开辟了尚未探索的领域。