The paper presents the first application of deep eutectic solvents (DES) as stationary phases for gas chromatography. DES obtained by mixing tetrabutylammonium chloride (TBAC) as a hydrogen bond acceptor (HBA) with heptadecanoic acid being a hydrogen bond donor (HBD) in a mole ratio of HBA:HBD equal to 1:2 was characterized by its ability to separate volatile organic compounds (VOCs). The Rohrschneider – McReynolds constants determined reveal that the synthesized DES is a stationary phase of medium polarity. A detailed retention characteristic was determined for a number of groups of chemical compounds, including aromatic hydrocarbons, alcohols, ketones, sulfides and thiophene derivatives. The synthesized DES was found to have a high selectivity towards alcohols. At the same time, the investigated stationary phase was found to have specific interactions with some analytes. For example, a stronger retention was observed for 1-hexanol and 1-heptanol compared to other alcohols. Retention times of these two alcohols are longer by 191% and 300%, respectively, relative to the expected value based on their boiling point. Such an increased retention is caused by a synergistic effect of various kinds of interactions – the possibility of formation of hydrogen bonds between the DES and the hydroxyl group of alcohols and hydrophobic interactions of alkyl chains of the DES with the alkyl chain of alcohols. The ability to modify properties of DESs by replacement of HBA or HBD with a different chemical compound or by dissolving in DES macromolecular substances makes the proposed stationary phase highly flexible. In addition to using the developed DES in chromatographic techniques, the retention data collected indicate the possibility of its application to other separation techniques, i.e. extractive distillation.

本文介绍了深共熔溶剂（DES）作为气相色谱固定相的首次应用。通过将HBA：HBD摩尔比等于1：2混合作为氢键受体（HBA）的四丁基氯化铵（TBAC）和作为氢键供体（HBD）的十六烷酸而获得的DES的特征在于其分离挥发性有机物的能力化合物（VOC）。测定的Rohrschneider-McReynolds常数表明合成的DES是中等极性的固定相。确定了许多化合物的详细保留特性，包括芳香烃，醇，酮，硫化物和噻吩衍生物。发现合成的DES对醇具有高选择性。同时，发现所研究的固定相与某些分析物具有特定的相互作用。例如，与其他醇相比，观察到1-己醇和1-庚醇的保留力更高。相对于基于它们的沸点的预期值，这两种醇的保留时间分别长191％和300％。保留时间的增加是由各种相互作用的协同作用引起的– DES与醇的羟基之间可能形成氢键，以及DES烷基链与醇的烷基链之间发生疏水相互作用。通过用不同的化合物替代HBA或HBD或溶解在DES大分子物质中来修饰DES的特性的能力使所提出的固定相具有高度的灵活性。