Radiation-induced damage of the upper gastrointestinal (GI) tract results from radiation of GI tumors or structures adjacent to the GI tract. Radiation-induced damages of the upper GI tract may be acute or delayed, and ranges from lack of appetite, mucosal inflammation (i.e. esophagitis, gastritis, duodenitis) to ulcers, which may be complicated by perforation, penetration, bleeding and stenosis. Radiation-related factors as well as individual patient predisposing factors may increase susceptibility to post-radiation damage. High quality evidence for the treatment of radiation-induced GI damage is scarce and the management is often extrapolated from studies on GI lesions of different etiology. Treatment depends on severity and localization of the radiation-induced damage, and ranges from supportive and dietary measures to endoscopic interventions or surgery. Modern radiation techniques may decrease the incidence and severity of the radiation-induced upper gastrointestinal disease.

辐射诱发的上消化道（GI）损伤是由GI肿瘤或与GI道相邻的结构辐射所致。辐射诱发的上消化道损害可能是急性的或延迟的，其范围从食欲不振，粘膜炎症（例如食管炎，胃炎，十二指肠炎）到溃疡，溃疡可能因穿孔，穿透，出血和狭窄而变得复杂。辐射相关因素以及个别患者的诱发因素可能会增加对辐射后损伤的易感性。放射治疗的胃肠道损伤治疗的高质量证据很少，并且通常根据对不同病因的胃肠道损伤的研究来推断治疗方法。治疗方法取决于辐射引起的损害的严重程度和局部性，范围从支持性和饮食性措施到内窥镜干预或手术。现代放射技术可降低放射诱发的上消化道疾病的发生率和严重程度。