Expression pattern of aluminum (Al) tolerance genes is one of the major determinants of Al avoidance/tolerance within plant cultivars. We have performed transcriptome analysis of two contrasting (Al-tolerant, Disang; Al-sensitive, Joymati) cultivars of India's North Eastern region, an indica rice diversity hotspot, on exposure to excess Al3+ treatment in acidic condition. Co-expression analysis and SNPs enrichment analysis proposed the role of both trans-acting and cis-acting polymorphisms in Al signaling in the Al-tolerant cultivar. We proposed ten major genes, including arginine decarboxylase, phytase, and beta-glucosidase aggregating factor as candidates responsible for Al tolerance based on transcriptome analysis. Al3+ stress led to changes in the alternative splicing profile of the Al-tolerant cultivar. These studies demonstrated the transcriptional variations affiliated to Al avoidance/tolerance in contrasting indica rice of North East India and provided us with several candidate genes responsible for Al tolerance.

中文翻译：

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根的比较 RNA-Seq 分析揭示了印度东北部对比籼稻中铝耐受性的转录调控系统

铝 (Al) 耐受基因的表达模式是植物栽培品种内铝避免/耐受的主要决定因素之一。我们对印度东北地区（籼稻多样性热点）的两个对比（耐铝、Disang；铝敏感、Joymati）栽培品种进行了转录组分析，这些栽培品种在酸性条件下暴露于过量的 Al3+ 处理。共表达分析和 SNP 富集分析提出了反式作用和顺式作用多态性在铝耐受品种中铝信号传导中的作用。我们基于转录组分析提出了十个主要基因，包括精氨酸脱羧酶、植酸酶和 β-葡萄糖苷酶聚集因子作为负责铝耐受的候选基因。Al3+ 胁迫导致耐铝品种的可变剪接谱发生变化。