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Coronary Artery Disease in Patients with HIV Infection: An Update
American Journal of Cardiovascular Drugs ( IF 2.8 ) Pub Date : 2020-11-13 , DOI: 10.1007/s40256-020-00451-9
Amish A Patel 1, 2 , Matthew J Budoff 1
Affiliation  

Premature cardiovascular disease among the HIV-infected population is of great concern among clinicians. The increased life expectancy of HIV-infected individuals is mainly due to the early detection of infection and the advent of antiretroviral therapy. Once known as a deadly disease, HIV infection has transitioned into a chronic condition. Cardiovascular disease in this population is thought to progress early due to traditional and non-traditional risk factors. Early detection of subclinical atherosclerosis has become a center of focus in research as our complete understanding of this process it not yet well known. Advancements in cardiac computed tomography angiography has enabled the exploration of coronary artery disease by further evaluation of coronary stenosis and plaque analysis. An increase in cardiovascular event rates in this population is currently thought to be linked to antiretroviral therapy, Framingham risk factors, and HIV. We sought to present an updated comprehensive review of the available literature on HIV related to atherosclerosis and cardiovascular risk.



中文翻译:

HIV 感染患者的冠状动脉疾病:最新进展

HIV感染人群中的过早心血管疾病是临床医生非常关注的问题。HIV感染者的预期寿命增加主要是由于早期发现感染和抗逆转录病毒疗法的出现。曾经被称为致命疾病的艾滋病毒感染已转变为慢性病。由于传统和非传统风险因素,该人群的心血管疾病被认为较早进展。亚临床动脉粥样硬化的早期检测已成为研究的焦点,因为我们对该过程的完全了解尚不为人所知。心脏计算机断层扫描血管造影的进步使得通过进一步评估冠状动脉狭窄和斑块分析来探索冠状动脉疾病成为可能。目前认为该人群心血管事件发生率的增加与抗逆转录病毒治疗、弗雷明汉危险因素和 HIV 相关。我们试图对现有的与动脉粥样硬化和心血管风险相关的 HIV 文献进行更新的全面回顾。

更新日期:2020-11-13
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