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Enrichment of retinal ganglion and Müller glia progenitors from retinal organoids derived from human induced pluripotent stem cells - possibilities and current limitations.
World Journal of Stem Cells ( IF 3.6 ) Pub Date : 2020-11-13 , DOI: 10.4252/wjsc.v12.i10.1171
Kristine Karla Freude , Sarkis Saruhanian , Alanna McCauley , Colton Paterson , Madeleine Odette , Annika Oostenink , Poul Hyttel , Mark Gillies , Henriette Haukedal , Miriam Kolko

Retinal organoids serve as excellent human-specific disease models for conditions affecting otherwise inaccessible retinal tissue from patients. They permit the isolation of key cell types affected in various eye diseases including retinal ganglion cells (RGCs) and Müller glia.

中文翻译:

从人诱导的多能干细胞衍生的视网膜类动物体中富集视网膜神经节和Müller胶质祖细胞-可能性和当前的局限性。

对于影响患者否则无法进入的视网膜组织的疾病,视网膜类器官可作为出色的人类特异性疾病模型。它们可以分离出受各种眼部疾病影响的关键细胞类型,包括视网膜神经节细胞(RGC)和Müller胶质细胞。
更新日期:2020-11-14
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