The functionalization of gold nanoparticles as a novel platform for the highly efficient electrochemical detection of silver ions,Analyst

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The functionalization of gold nanoparticles as a novel platform for the highly efficient electrochemical detection of silver ions
Analyst ( IF 3.6 ) Pub Date : 2020-10-30 , DOI: 10.1039/d0an01870h
Zhourui Xiao _{1,

2,

3,

4} , Han Meng _{1,

2,

3,

4} , Xuefei Qin _{1,

2,

3,

4} , Xueqing Sang _{1,

2,

3,

4} , Yun Zhang _{1,

2,

3,

4} , Yali Yuan _{1,

2,

3,

4}

Affiliation

Herein, a novel electrochemical biosensor was constructed for the highly efficient detection of silver ions. A porous platform constructed with functionalized gold nanoparticles (AuPP) was electropolymerized on the gold electrode surface. The obtained polymer, analogous to a metal–organic framework, was used as the sensing platform together with cytosine–Ag⁺–cytosine interaction for dual signal amplification. The scanning electron microscopy (SEM) image of the AuPP platform exhibited a porous structure and considerable binding sites for C-riched single stranded DNA, leading to predictable silver ion preconcentration. Based on this strategy, the biosensor showed that the peak current in differential pulse voltammetry rose linearly as the concentration of silver ion increased from 0.005 to 3 μM with a detection limit of 1.3 nM. In addition, in the presence of other metal ions, such as Pb²⁺, Mn²⁺, Ni²⁺, Co²⁺, Cu²⁺, Zn²⁺, Na⁺, Ca²⁺, and Cd²⁺, at the same concentration, the current signal remained almost unchanged, manifesting high selectivity for Ag⁺. This proposed sensor might exhibit a novel fabrication method for metal ion detection with the aid of multiple AuPP materials by designing ligands with different functional groups.

中文翻译：

金纳米颗粒的功能化作为高效电化学检测银离子的新平台

在此，构建了用于高效检测银离子的新型电化学生物传感器。在金电极表面上电聚合由功能化金纳米颗粒（AuPP）构成的多孔平台。所得的类似于金属-有机骨架的聚合物与胞嘧啶-Ag ⁺一起用作传感平台–胞嘧啶相互作用，用于双重信号放大。AuPP平台的扫描电子显微镜（SEM）图像显示出多孔结构和富含C的单链DNA的大量结合位点，导致可预测的银离子预富集。基于此策略，生物传感器显示，随着银离子浓度从0.005增至3μM，检测限为1.3 nM，差动脉冲伏安法中的峰值电流呈线性上升。另外，在其他金属离子的存在下，例如Pb 2 ⁺，Mn 2 ⁺，Ni 2 ⁺，Co 2 ⁺，Cu 2 ⁺，Zn 2 ⁺，Na ⁺，Ca ²⁺和Cd ²⁺在相同浓度下，电流信号几乎保持不变，表明对Ag ⁺具有高选择性。通过设计具有不同官能团的配体，该拟议的传感器可能展示出一种借助多种AuPP材料进行金属离子检测的新颖制造方法。

更新日期：2020-11-12

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