Imines, versatile intermediates for organic synthesis, can be exploited for the preparation of diverse classes of biologically active benzazoles. Because of the special characteristics of the C=N bond, imines can be simultaneously used in the synthesis of 1,3-benzazoles and 1,2-benzazoles. With the development of imine synthesis, a variety of novel cascade reactions for benzazole synthesis have been reported in the last decade. Therefore, there is a strong need to elucidate the recent progress in the formation of various classes of benzazoles, including benzimidazoles, benzoxazoles, benzothiazoles, indazoles, and benzisoxazoles, via imines obtained by condensation reactions or oxidative/ redox coupling reactions

亚胺是有机合成的通用中间体，可用于制备各种类型的具有生物活性的苯并恶唑。由于C = N键的特殊特性，亚胺可同时用于1,3-苯并恶唑和1,2-苯并恶唑的合成。随着亚胺合成的发展，在过去的十年中已经报道了多种用于苯并唑合成的新颖的级联反应。因此，迫切需要阐明通过缩合反应或氧化/氧化还原偶联反应得到的亚胺形成各种类型的苯并恶唑的最新进展，包括苯并咪唑，苯并恶唑，苯并噻唑，吲唑和苯并异恶唑。