Molecular rearrangements are important tools to increase the molecular diversity of new bioactive compounds, especially in the class of heterocycles. This review deals specifically with a very famous and widely applicable rearrangement known as the Dimroth Rearrangement. Although it has originally been observed for 1,2,3-triazoles, its amplitude was greatly expanded to other heterocycles, as well as from laboratory to large scale production of drugs and intermediates. The reactions that were discussed in this review were selected with the aim of demonstrating the windows that may be open by the Dimroth's rearrangement, especially in what regards the development of new synthetic approaches toward biologically active compounds.

分子重排是增加新的生物活性化合物的分子多样性的重要工具，尤其是在杂环类中。这篇评论专门针对一种非常著名且广泛应用的重排，称为Dimroth重排。尽管最初观察到1,2,3-三唑的情况，但其幅度已大大扩展到其他杂环，以及从实验室到大规模生产药物和中间体的过程。选择本综述中讨论的反应是为了证明Dimroth的重排可能会打开的窗口，特别是在开发针对生物活性化合物的新合成方法方面。