当前位置: X-MOL 学术Dubai Diabetes Endocrinol. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Pattern, Trend and Predictors of Adult-Onset Type 1 Diabetes in Uyo, Nigeria
Dubai Diabetes and Endocrinology Journal Pub Date : 2020-10-22 , DOI: 10.1159/000511242
Collins Amadi , Olufisayo G. Ayoade , Samuel I. Onung , Sarah I. Essien , Anietie A. Etuk , Chidozie J. Okafor

Background: Unlike what obtains in childhood-onset type 1 diabetes, there remains a paucity of data on adult-onset type 1 diabetes in Nigeria. Hence, the current study aimed to determine the general characteristics of adult-onset type 1 diabetes among subjects (aged ≥18 years) presenting at the University of Uyo Teaching Hospital (UUTH) in Akwa Ibom State, South-south Nigeria. Methods: A 5-year (2014–2018) retrospective records review of subjects with type 1 diabetes was undertaken, using hospital medical records retrieved from the Department of Health Information Management of UUTH. Diagnosed adult cases of type 1 diabetes were meticulously identified and the relevant data at the point of initial diagnosis were acquired on a specially designed data acquisition template. Results: A total of 47,357 medical cases were identified of which 362 adults were diagnosed with type I diabetes (mean age 33.12 ± 4.40, range 20–51 years) and the females (n = 204; 56.4%) predominated among those diagnosed. The overall, male gender, and female gender prevalence was 7.4/1,000 (95% confidence interval [CI]: 6.89–7.98), 3.3/1,000 (95% CI: 2.52–4.08), and 4.3/1,000 (95% CI: 3.61–4.99), respectively. The females exhibited the highest trough, peak, annual, and overall prevalence during the study period. The female gender (OR: 2.334; 95% CI: 1.407–3.478; p = 0.010), age ≤30 years (OR: 1.976; 95% CI: 0.875–3.211; p #x3c; 0.001), urban-dwelling (OR: 3.243; 95% CI: 2.3407.780; #x3c;0.001), diabetes family history (OR: 1.365; 95% CI: 0.678–2.010; p = 0.033), and the rainy season (OR: 1.129; 95% CI: 0.401–1.910; p #x3c; 0.001) were independent predictors among the overall adult type 1 diabetics. On gender-segregated analyses, age ≤30 years, urban-dwelling, diabetes family history, and the rainy season remained independent predictors among the male and female adult type 1 diabetics (p #x3c; 0.05). Conclusion: The study demonstrated a high burden of type 1 diabetes among adult residents of Uyo, Akwa Ibom State, South-South Nigeria. The predictors of adult type 1 diabetes, identified in the present study, are valuable epidemiologic evidence for the design of type 1 diabetes-targeted preventive programs by various concerned stakeholders.
Dubai Diabetes Endocrinol J


中文翻译:

尼日利亚乌约的成人1型糖尿病的类型,趋势和预测因素

背景:与在儿童期1型糖尿病中获得的数据不同,在尼日利亚,关于成人1型糖尿病的数据仍然很少。因此,本研究旨在确定在尼日利亚南南阿克瓦伊博姆州乌约大学教学医院(UUTH)的大学(≥18岁)受试者中成人1型糖尿病的一般特征。方法:使用从UUTH的健康信息管理部门获得的医院病历,对1型糖尿病受试者进行了为期5年(2014-2018年)的回顾性记录回顾。精心识别已诊断的成人1型糖尿病病例,并在特别设计的数据采集模板上采集初次诊断时的相关数据。结果:总共鉴定出47,357例医疗病例,其中362名被诊断为I型糖尿病的成年人(平均年龄33.12±4.40,范围为20-51岁),而女性(n = 204; 56.4%)居首位。总体,男性和女性患病率分别为7.4 / 1,000(95%置信区间[CI]:6.89–7.98),3.3 / 1,000(95%CI:2.52–4.08)和4.3 / 1,000(95%CI: 3.61–4.99)。在研究期间,雌性的谷值,高峰,年度和总体患病率最高。女性,市区居民(OR :2.334; 95%CI:1.407–3.478; p = 0.010),年龄≤30岁(OR:1.976; 95%CI:0.875–3.211; p#x3c; 0.001) :3.243; 95%CI:2.3407.780;#x3c; 0.001),糖尿病家族史(OR:1.365; 95%CI:0.678-2.010;p = 0.033)和雨季(OR:1.129; 95%CI:0.401–1.910;p#x3c; 0.001)是整个成年1型糖尿病患者的独立预测因子。在按性别分类的分析中,年龄≤30岁,城市居民,糖尿病家族史和雨季仍然是成年1型男性和女性糖尿病患者的独立预测因子(p#x3c; 0.05)。结论:该研究表明尼日利亚南部和南部阿克瓦伊博姆州乌约市成年居民的1型糖尿病负担很高。在本研究中确定的成人1型糖尿病的预测因素,是有关各方设计1型糖尿病为目标的预防计划的有价值的流行病学证据。
迪拜糖尿病内分泌J
更新日期:2020-11-12
down
wechat
bug