Abstract

Wriggling call produced by mouse pups when struggling in the nest is one of the mouse early ontogenesis communicative vocalization. Processing of these signals by auditory midbrain and primary auditory cortex neurons with different response patterns was the subject of this study. Responses of single neurons evoked by wriggling call models and a series of models consisting of 4 stimuli with different interstimulus intervals (0–1000 ms) were recorded extracellularly. A third of central nucleus neurons in the inferior colliculus showed a spectral facilitation in responses to various two- and three-tone combinations of the wriggling call frequency components. About 80% of such combination-sensitive neurons had tonic characteristics of responses, i.e. tonic, phasic-tonic, pauser and long-latency discharges. A study of responses of central nucleus neurons to a series of wriggling call models showed that at short interstimulus intervals (0–50 ms) responses to the 2nd–4th signals in a series were completely suppressed or significantly decreased in two-thirds of the recorded neurons, i.e. there arose adaptation to a series of sounds. Such neurons had mainly phasic discharges. In a third of neurons, adaptation did not arise; these neurons were tonically discharging. All neurons in the primary auditory cortex (anterior and primary auditory fields) demonstrated adaptation in responses to a series of wriggling calls. Discharges of neurons were phasic.

中文翻译：

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通讯呼叫处理过程中小鼠小家鼠听觉中脑和原发听觉皮层中不同反应模式的神经元的特化

摘要

小鼠幼崽在巢中挣扎时产生的蠕动回叫是小鼠早期本体发生的交流发声之一。本研究的主题是由具有不同响应模式的听觉中脑和初级听觉皮层神经元处理这些信号。在细胞外记录了蠕动的呼叫模型和一系列由4个具有不同刺激间隔（0-1000 ms）的刺激组成的模型所诱发的单个神经元的反应。下丘的中枢神经中枢神经元的三分之一显示出频谱上的促进，响应了蠕动的呼叫频率分量的各种二音和三音组合。大约80％的此类组合敏感神经元具有反应的强直特征，即强直，相声，停顿和长时延放电。对中央核神经元对一系列蠕动调用模型的响应的研究表明，在短的刺激间隔（0–50 ms）中，一系列记录中对第二至第四信号的响应被完全抑制或显着降低神经元，即出现了对一系列声音的适应。这样的神经元主要具有相放电。在三分之一的神经元中，没有出现适应。这些神经元在紧张地放电。初级听觉皮层（前和初级听觉场）中的所有神经元均表现出对一系列蠕动性呼唤的适应性。神经元放电是阶段性的。