Construct validity of novel tablet-based neurocognitive tests (in the NeuroScreen app) measuring processing speed, working memory, and executive functioning in adolescents and young adults (AYA) living with perinatally-acquired HIV (PHIV) and perinatal HIV-exposure without infection (PHEU) was examined. Sixty-two AYA (33 PHIV, 29 PHEU) were recruited from an ongoing longitudinal study (CASAH) in New York City. Medium to large and statistically significant correlations were found between NeuroScreen and gold standard, paper-and-pencil tests of processing speed, working memory, and executive functioning. Results provide partial support for NeuroScreen as an alternative to cumbersome paper-and-pencil tests for assessing neurocognition among HIV-affected AYA.

构建新型基于平板电脑的神经认知测试（在NeuroScreen应用程序中）的有效性，测量患有围产期获得性 HIV（PHIV）和围产期 HIV 暴露无感染的青少年和年轻人（AYA）的处理速度、工作记忆和执行功能。 PHEU) 进行了检查。从纽约市正在进行的纵向研究 (CASAH) 中招募了 62 名 AYA（33 名 PHIV，29 名 PHEU）。在NeuroScreen和黄金标准、处理速度、工作记忆和执行功能的纸笔测试之间发现了中到大且具有统计学意义的相关性。结果为NeuroScreen提供了部分支持，可以替代繁琐的纸笔测试，以评估受 HIV 影响的 AYA 的神经认知。