Malignant tumor is a largely harmful disease worldwide. The cure rate of malignant tumors increases with the continuous discovery of anti-tumor drugs and the optimisation of chemotherapy options. However, drug resistance of tumor cells remains a massive obstacle in the treatment of anti-tumor drugs. The heterogeneity of malignant tumors makes studying it further difficult for us. In recent years, using single-cell sequencing technology to study and analyse circulating tumor cells can avoid the interference of tumor heterogeneity and provide a new perspective for us to understand tumor drug resistance.

中文翻译：

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单细胞测序在肿瘤异质性及循环肿瘤细胞耐药性中的研究及应用


恶性肿瘤是世界范围内危害极大的疾病。随着抗肿瘤药物的不断发现和化疗方案的优化，恶性肿瘤的治愈率不断提高。然而，肿瘤细胞的耐药性仍然是抗肿瘤药物治疗的巨大障碍。恶性肿瘤的异质性给我们进一步研究带来了困难。近年来，利用单细胞测序技术研究分析循环肿瘤细胞，可以避免肿瘤异质性的干扰，为我们了解肿瘤耐药性提供了新的视角。