Background: Recent evidence has indicated that long non-coding RNAs (lncRNAs) were emerged as key molecules in clear cell renal cell carcinoma (ccRCC). TCGA database showed that the expression level of lncRNA NLGN1-AS1 was up-regulated in ccRCC; However, whether NLGN1-AS1 implicated in the malignant progression of ccRCC remained unclear.

中文翻译：

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lncRNA NLGN1-AS1 和 Wnt 信号传导的调节回路通过 FZD4 调节的途径控制透明细胞肾细胞癌表型


背景：最近的证据表明，长非编码 RNA (lncRNA) 已成为透明细胞肾细胞癌 (ccRCC) 的关键分子。 TCGA数据库显示lncRNA NLGN1-AS1在ccRCC中表达水平上调；然而，NLGN1-AS1是否与ccRCC的恶性进展有关仍不清楚。