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Global miRNA to miRNA Interactions: Impacts for miR-21
Trends in Cell Biology ( IF 13.0 ) Pub Date : 2020-11-11 , DOI: 10.1016/j.tcb.2020.10.005 Meredith Hill 1 , Nham Tran 2
中文翻译:
全球 miRNA 与 miRNA 的相互作用:对 miR-21 的影响
更新日期:2020-12-17
Trends in Cell Biology ( IF 13.0 ) Pub Date : 2020-11-11 , DOI: 10.1016/j.tcb.2020.10.005 Meredith Hill 1 , Nham Tran 2
Affiliation
miRNAs inherently alter the cellular environment by regulating target genes. miRNAs may also regulate other miRNAs, with far-reaching influence on miRNA and mRNA expression. We explore this realm of small RNA regulation with a focus on the role of the oncogenic miR-21 and its impact on other miRNA species.
中文翻译:
全球 miRNA 与 miRNA 的相互作用:对 miR-21 的影响
miRNA 通过调节靶基因来固有地改变细胞环境。miRNAs 还可以调节其他 miRNAs,对 miRNA 和 mRNA 的表达产生深远的影响。我们探索了小 RNA 调控的这一领域,重点是致癌 miR-21 的作用及其对其他 miRNA 物种的影响。