Abstract In this study the densities (ρ), speeds of sound (u) and viscosities ( η ) of L-histidine and L-serine in water and in aqueous levofloxacin solutions at different concentrations and over a wide range of temperature T = (293.15 - 313.15) K have been measured. The experimental data is used to calculate the apparent molar volume ( V ϕ ), apparent molar isentropic compression ( K ϕ , s ), limiting apparent molar volume ( V o ϕ ) and limiting apparent molar isentropic compression ( K ° ϕ , s ) for the studied amino acid. The limiting apparent molar expansivity ( E ° ϕ ) of solute and Helpers constant are also evaluated. The transfer parameters like transfer volumes ( Δ tr V ° ϕ ) and transfer compressibility ( Δ tr K ° ϕ , S ) are also evaluated. The viscosity data has been used to evaluate the viscosity B coefficients. Also the free energy parameters like change in free energy of the solute and solvent has been evaluated. The above mentioned results are interpreted in terms of solute-solute / solute-solvent interaction and structure making / breaking characteristics of solute in the aqueous antibiotics solution.

中文翻译：

---

在不同温度和浓度下左氧氟沙星水溶液中 L-组氨酸和 L-丝氨酸的体积、声学和粘度研究

摘要 在这项研究中，L-组氨酸和 L-丝氨酸在水和左氧氟沙星水溶液中不同浓度和很宽的温度范围内的密度 (ρ)、声速 (u) 和粘度 (η) T = (293.15 - 313.15) K 已被测量。实验数据用于计算表观摩尔体积 ( V ϕ )、表观摩尔等熵压缩 ( K ϕ , s )、限制表观摩尔体积 ( V o ϕ ) 和限制表观摩尔等熵压缩 ( K ° ϕ , s )研究的氨基酸。还评估了溶质和辅助常数的极限表观摩尔膨胀率 ( E ° ϕ )。还评估了传输参数，如传输体积 ( Δ tr V ° ϕ ) 和传输压缩率 ( Δ tr K ° ϕ , S )。粘度数据已用于评估粘度 B 系数。还评估了自由能参数，如溶质和溶剂的自由能变化。上述结果是根据溶质-溶质/溶质-溶剂相互作用和抗生素水溶液中溶质的结构形成/破坏特性来解释的。