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General health and mortality in Tourette syndrome and chronic tic disorder: A mini-review
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2020-11-11 , DOI: 10.1016/j.neubiorev.2020.11.005
Lorena Fernández de la Cruz 1 , David Mataix-Cols 1
Affiliation  

Current knowledge on the general somatic health and causes of death in Tourette syndrome and chronic tic disorder is very limited. Here, we review the available literature on the topic, while highlighting strengths and weaknesses of the studies conducted to date. These previous works have suggested associations between Tourette syndrome and chronic tic disorder and a range of health conditions, including autoimmune disorders, common allergies and respiratory diseases, sleep difficulties, and metabolic and cardiovascular outcomes. Additionally, the risk of mortality in tic disorders might be higher than that of the general population, but specific causes of death have rarely been studied, except for substance use-related deaths and suicide, which are significantly higher in individuals with Tourette syndrome and chronic tic disorder. Many of these emerging findings require replication and extension but, taken together, they suggest that that it might be sensible to monitor the general health and suicide risk of individuals with Tourette syndrome or chronic tic disorder across the lifespan. We suggest further avenues for research on this topic.



中文翻译:

抽动秽语综合征和慢性抽动症的一般健康和死亡率:小型回顾

关于抽动秽语综合征和慢性抽动症的总体身体健康和死亡原因的当前知识非常有限。在这里,我们回顾了有关该主题的现有文献,同时强调了迄今为止进行的研究的优缺点。这些先前的研究表明,抽动秽语综合征和慢性抽动症与一系列健康状况之间存在关联,包括自身免疫性疾病,常见过敏和呼吸系统疾病,睡眠困难以及代谢和心血管疾病。此外,抽动障碍的死亡风险可能高于一般人群,但是除了与物质使用相关的死亡和自杀外,很少研究具体的死亡原因,在图雷特综合症和慢性病患者中,这种死亡风险明显更高。抽动症。这些新兴发现中有许多都需要复制和扩展,但综合起来,他们认为在整个生命周期中监测图雷特综合征或慢性抽动症患者的总体健康和自杀风险可能是明智的。我们建议对该主题进行进一步研究。

更新日期:2020-11-12
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