Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2020-09-30 , DOI: 10.2174/1389557520666200624193300 Maria Beatriz Silva Costa 1 , Camila Martins de Oliveira 2
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Neglected tropical diseases are a serious global public health problem and they are one of the main causes of mortality and morbidity, especially in underdeveloped countries. These diseases have several implications for health and they are considered a priority in global eradication programs for disease control. The aim of this mini-review is to report recent studies on the fight against neglected diseases, namely dengue fever, chikungunya, zika, malaria protozoa, Chagas disease, leishmaniasis, schistosomiasis helminths, filariasis, and tuberculosis bacteria using extracts and isolated substances of endophytic fungi based on their bioactivity profiles in relation to these diseases.
中文翻译：
内生真菌与热带病的抗争
被忽视的热带病是一个严重的全球性公共卫生问题，是造成死亡和发病的主要原因之一，特别是在不发达国家。这些疾病对健康有若干影响，在全球疾病控制的根除计划中，它们被视为优先事项。本小报告的目的是报告使用提取物和分离出的内生物质与登革热，基孔肯雅热，寨卡病毒，疟原虫，南美锥虫病，利什曼病，血吸虫病，蠕虫病，丝虫病和肺结核细菌等被忽视疾病作斗争的最新研究真菌基于与这些疾病有关的生物活性概况。
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