Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Peptide-Mediated Synthesis of Zeolitic Imidazolate Framework-8 with Controllable Morphology and Size
Langmuir ( IF 3.7 ) Pub Date : 2020-11-11 , DOI: 10.1021/acs.langmuir.0c02496 Jiaming Xuan 1 , Yang Liu 1 , Xiaomin Xu 1 , Zhen Ding 1 , Ziwei Zhuang 1 , Yuxin Zhang 1 , Yunpeng Yan 1 , Meiwen Cao 1 , Shengjie Wang 1 , Yongqing Xia 1 , Li Sun 2
Langmuir ( IF 3.7 ) Pub Date : 2020-11-11 , DOI: 10.1021/acs.langmuir.0c02496 Jiaming Xuan 1 , Yang Liu 1 , Xiaomin Xu 1 , Zhen Ding 1 , Ziwei Zhuang 1 , Yuxin Zhang 1 , Yunpeng Yan 1 , Meiwen Cao 1 , Shengjie Wang 1 , Yongqing Xia 1 , Li Sun 2
Affiliation
|
Peptides with a sequence of Nap-Ix-GPLGLAG-R4-NH2 (x = 2, 4, and 6, shorted as I2R4, I4R4, and I6R4) were used as capping agents for the synthesis of zeolitic imidazolate framework-8 (ZIF-8) in water. Peptide addition can significantly inhibit the growth of ZIF-8 crystals. The shape and size of ZIF-8 crystals was related closely to the number of isoleucine (Ile, I) residues as well as concentration of the peptide. The shape of ZIF-8 crystals changes from rhomboid dodecahedron to truncated rhombic dodecahedron to cube with the decreasing number of isoleucine residues from six to two. At a peptide concentration of 1.0 mM, the morphology of ZIF-8 crystals was cubic, truncated rhombic dodecahedron, and typical rhombic dodecahedron in the cases of I2R4, I4R4, and I6R4, respectively. Also, the particle size can be regulated from ca. 1.7 μm to <100 nm by controlling the peptide concentration from 0 to 2.0 mM. This work develops a simple and green method for the synthesis of ZIF-8 crystals with controllable shape and size in water, which shows high potential for biomedical and biological applications.
中文翻译：
肽介导的形态和尺寸可控的沸石咪唑盐骨架8的合成
具有Nap-I x -GPLGLAGAG-R 4 -NH 2（x = 2、4和6）序列的肽，简称为I 2 R 4，I 4 R 4和I 6 R 4）用作封端剂，用于在水中合成沸石咪唑酯骨架8（ZIF-8）。肽的添加可以显着抑制ZIF-8晶体的生长。ZIF-8晶体的形状和大小与异亮氨酸（Ile，I）残基的数量以及肽的浓度密切相关。ZIF-8晶体的形状从菱形十二面体变为截短的菱形十二面体，变为立方，异亮氨酸残基的数量从六个减少到两个。在I 2 R 4，I 4 R 4和I 6 R 4的情况下，在肽浓度为1.0 mM时，ZIF-8晶体的形态为立方，截头菱形十二面体和典型的菱形十二面体。， 分别。同样，可以从约100nm调节粒径。通过将肽浓度控制在0至2.0 mM之间，可将1.7μm降至<100 nm。这项工作开发了一种简单且绿色的方法来合成ZIF-8晶体，该晶体在水中的形状和大小可控，在生物医学和生物应用中显示出很高的潜力。
更新日期：2020-11-25
中文翻译：
肽介导的形态和尺寸可控的沸石咪唑盐骨架8的合成
具有Nap-I x -GPLGLAGAG-R 4 -NH 2（x = 2、4和6）序列的肽，简称为I 2 R 4，I 4 R 4和I 6 R 4）用作封端剂，用于在水中合成沸石咪唑酯骨架8（ZIF-8）。肽的添加可以显着抑制ZIF-8晶体的生长。ZIF-8晶体的形状和大小与异亮氨酸（Ile，I）残基的数量以及肽的浓度密切相关。ZIF-8晶体的形状从菱形十二面体变为截短的菱形十二面体，变为立方，异亮氨酸残基的数量从六个减少到两个。在I 2 R 4，I 4 R 4和I 6 R 4的情况下，在肽浓度为1.0 mM时，ZIF-8晶体的形态为立方，截头菱形十二面体和典型的菱形十二面体。， 分别。同样，可以从约100nm调节粒径。通过将肽浓度控制在0至2.0 mM之间，可将1.7μm降至<100 nm。这项工作开发了一种简单且绿色的方法来合成ZIF-8晶体，该晶体在水中的形状和大小可控，在生物医学和生物应用中显示出很高的潜力。
京公网安备 11010802027423号