Sclerosing angiomatoid nodular transformation (SANT) is a rare splenic lesion first described by Martel et al in 2004.1 As reported, SANT is a benign vascular lesion of the red pulp of the spleen, presenting under the microscope as angiomatoid nodules in a fibrosclerotic stroma. Although more than 200 cases have been reported in the English literature,2 only 8 cases have been found in children. SANT is most often suspected from imaging studies performed for another reason. Nevertheless, no signs are specific.3 This motivates surgery to remove the mass and confirm the diagnosis. The surgery could be done either by open, laparoscopic partial or total splenectomy.4 Herein, we reported two pediatric cases of SANT that were well treated by laparoscopic total and partial splenectomy. A 14-year-old girl was referred to our pediatric surgery department for further investigations of a solid tumor of the spleen. The mass was diagnosed by a routine ultrasonography (US) performed in the pediatric endocrinology department in the context of urinary tract infection and chronic asthenia. The patient’s medical and family history was unremarkable. On physical examination, she had good general condition without anorexia, fever or night sweats. Neither hepatosplenomegaly nor lymphadenopathies were found. The patient’s blood tests showed anemia (hemoglobin 85 g/L) and increased inflammatory markers [C reactive protein (CRP): 18 mg/L and erythrocytes sedimentation rate (ESR): 40 mm/hour]. Abdominal US imaging found a calcified heterogeneous vascularized central splenic mass with a maximal diameter of 7 cm (figure 1A). The US finding was confirmed by an MRI which showed a splenic vascular tissular lesion that had an iso-intense signal on T2 sequence and a progressive signal enhancement of the central portion after injection (figure 1B). Two weeks prior to surgery, she was vaccinated against Streptococcus pneumoniae , Haemophilus influenzae , and Neisseria meningitidis …

中文翻译：

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小儿脾脏硬化性血管瘤样结节样变：腹腔镜脾脏全切或部分切除术2例并文献复习

硬化性血管瘤样结节性转化 (SANT) 是一种罕见的脾脏病变，由 Martel 等人于 2004 年首次描述。据报道，SANT 是脾脏红髓的良性血管病变，在显微镜下表现为纤维硬化间质中的血管瘤样结节。尽管在英文文献中已报道了 200 多例病例，2 但仅在儿童中发现了 8 例。由于其他原因进行的影像学检查最常怀疑 SANT。然而，没有具体的迹象。3 这促使手术切除肿块并确认诊断。手术可以通过开放式、腹腔镜部​​分或全脾切除术进行。4 在此，我们报告了两例 SANT 儿科病例，均通过腹腔镜全脾切除术和部分脾切除术得到了很好的治疗。一名 14 岁的女孩被转诊至我们的儿科外科，以进一步检查脾脏实体瘤。在尿路感染和慢性虚弱的情况下，通过在儿科内分泌科进行的常规超声检查 (US) 诊断出肿块。患者的医疗史和家族史均无异常。查体一般情况良好，无厌食、发热、盗汗。既没有发现肝脾肿大也没有发现淋巴结病。患者的血液检查显示贫血（血红蛋白 85 g/L）和炎症标志物升高 [C 反应蛋白 (CRP)：18 mg/L 和红细胞沉降率 (ESR)：40 mm/小时]。腹部超声成像发现钙化的异质血管化中央脾脏肿块，最大直径为 7 厘米（图 1A）。US 的发现得到了 MRI 的证实，该 MRI 显示脾脏血管组织病变在 T2 序列上具有等强度信号，并且在注射后中央部分信号逐渐增强（图 1B）。手术前两周，她接种了肺炎链球菌、流感嗜血杆菌和脑膜炎奈瑟菌……