We propose a chiral imaging modality based on optical chirality engineering, fluorescence-detected circular dichroism, and structured illumination microscopy. In this method, the optical chirality of the illumination is structured and the circular dichroism dependent fluorescence is detected. With image reconstruction, the spatial distribution of the chiral domains can be obtained at subdiffraction-limited resolution. We theoretically demonstrate this method and discuss the feasibility of using an optical chirality engineering approach based on far-field optics.

中文翻译：

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手性结构照明显微镜

我们提出了一种基于光学手性工程，荧光检测圆二色性和结构照明显微镜的手性成像方法。在这种方法中，构造照明的光学手性，并检测依赖于圆二色性的荧光。通过图像重建，可以在亚衍射极限分辨率下获得手性域的空间分布。我们从理论上证明了这种方法，并讨论了使用基于远场光学的光学手性工程方法的可行性。