Abstract

Cordyceps militaris has been reported to the diverse pharmaceutical effects including cancer, inflammatory diseases, and bacteria or virus infection. However, the effect of C. militaris on exercise performance has not yet been elucidated. In this study, we investigated the beneficial effect of C. militaris on exercise performance. To evaluate exercise performance, we prepared C. militaris ethyl acetate extract (CMEE) and conducted grip strength tests every week after administration. Additionally, blood samples were collected at the end of the experiment for biochemical analysis. The administration of CMEE slightly increased grip strength, and this result was similar to the red ginseng treated group. According to the result of biochemical analysis, CMEE had an effect on the biomarkers related to ATP generation pathway but had little influence on the muscle fatigue related biomarkers. Therefore, C. militaris has the possibility of improving exercise performance, which could be associated with the increase in ATP production rather than the decrease in muscle fatigue during exercise.

摘要

据报道，虫草具有多种药物作用，包括癌症，炎性疾病以及细菌或病毒感染。但是，尚未阐明游梭菌对运动表现的影响。在这项研究中，我们调查了C.militaris对运动表现的有益影响。为了评估运动表现，我们准备了C. militaris给药后每周进行乙酸乙酯提取物（CMEE）的抓地力测试。另外，在实验结束时收集血样用于生化分析。CMEE的施用略微增加了握力，这一结果与红参治疗组相似。根据生化分析的结果，CMEE对与ATP生成途径相关的生物标志物有影响，但对与肌肉疲劳相关的生物标志物影响很小。因此，C。militaris有可能改善运动表现，这可能与ATP产生的增加而不是运动过程中肌肉疲劳的减少有关。