Abstract

The coordination between the animal’s external environment and internal state requires constant modulation by chemicals known as neuromodulators. Neuromodulators, such as biogenic amines, neuropeptides and cytokines, promote organismal homeostasis. Over the past several decades, Caenorhabditis elegans has grown into a powerful model organism that allows the elucidation of the mechanisms of action of neuromodulators that are conserved across species. In this perspective, we highlight a collection of articles in this issue that describe how neuromodulators optimize C. elegans survival.

中文翻译：

---

神经调节剂：生存的重要组成部分

 抽象的

动物外部环境和内部状态之间的协调需要被称为神经调节剂的化学物质不断调节。神经调节剂，如生物胺、神经肽和细胞因子，可促进机体稳态。在过去的几十年里，秀丽隐杆线虫已经成长为一种强大的模式生物，可以阐明跨物种保守的神经调节剂的作用机制。从这个角度来看，我们重点介绍本期的一系列文章，这些文章描述了神经调节剂如何优化线虫的生存。