The persistent prevalence of cigarette smoking continues to contribute to preventable disease and death in the United States. Although much is known about the deleterious systemic effects of cigarette smoke and nicotine, some clinically relevant areas still remain unclear, such as the impact of cigarette smoke and nicotine on stem cells and the subsequent implications in regenerative medicine. This review focuses on recent studies on the effect of cigarette smoke and one of its deleterious components nicotine on mesenchymal stem cells, with an emphasis on dental stem cells.

中文翻译：

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香烟烟雾对间充质干细胞和牙干细胞影响的比较


在美国，吸烟的持续流行继续导致可预防的疾病和死亡。尽管人们对香烟烟雾和尼古丁的有害全身影响了解很多，但一些临床相关领域仍不清楚，例如香烟烟雾和尼古丁对干细胞的影响以及随后对再生医学的影响。本综述重点关注最近关于香烟烟雾及其有害成分之一尼古丁对间充质干细胞（特别是牙齿干细胞）影响的研究。