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The rise and fall of bone marrow plasma cells after influenza vaccination
Immunology and Cell Biology ( IF 4 ) Pub Date : 2020-11-09 , DOI: 10.1111/imcb.12417 Marios Koutsakos 1 , Ali H Ellebedy 2, 3
Immunology and Cell Biology ( IF 4 ) Pub Date : 2020-11-09 , DOI: 10.1111/imcb.12417 Marios Koutsakos 1 , Ali H Ellebedy 2, 3
Affiliation
A recent report by Davis et al. shows that following vaccination, B‐cell activation results in the emergence of a population of antibody‐secreting cells (plasmablasts – PBs) in blood and a population of plasma cells (PCs) in the bone marrow, which likely originate from the day 7 PBs. However, these newly arrived PCs do not become long‐lived and their abundance decreases by 1 year post‐vaccination.
中文翻译:
流感疫苗接种后骨髓浆细胞的升降
戴维斯等人最近的一份报告。表明接种疫苗后,B 细胞活化导致血液中出现抗体分泌细胞群(浆母细胞 - PB)和骨髓中出现浆细胞(PC)群,这可能起源于第 7 天 PB . 然而,这些新到达的 PC 不会变得长寿,并且在接种疫苗后 1 年它们的丰度会下降。
更新日期:2020-11-09
中文翻译:
流感疫苗接种后骨髓浆细胞的升降
戴维斯等人最近的一份报告。表明接种疫苗后,B 细胞活化导致血液中出现抗体分泌细胞群(浆母细胞 - PB)和骨髓中出现浆细胞(PC)群,这可能起源于第 7 天 PB . 然而,这些新到达的 PC 不会变得长寿,并且在接种疫苗后 1 年它们的丰度会下降。