On chip optofluidic low‐pressure monitoring device,Journal of Biophotonics

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On chip optofluidic low‐pressure monitoring device
Journal of Biophotonics ( IF 2.0 ) Pub Date : 2020-11-10 , DOI: 10.1002/jbio.202000381
Abhijit Chandra Roy ₁ , Shreyas Bangalore Subramanya ₂ , Shoorashetty Manohar Rudresh ₃ , Venkatakrishnan Venkataraman ₁

Affiliation

We present an on chip optofluidic surface deformable liquid Dove prism (LDP) based low‐fluid flow pressure monitoring device. The unique design of the device in combination with liquid and soft solid enabled by the total internal reflection of light makes the sensor highly sensitive and compatible with the integration of a microfluidic and/or Lab‐on‐a‐chip device. A layer‐by‐layer soft lithographic (LSL) and 3D printing technique are exploited to make the device. We have used Polydimethylsiloxane (PDMS) as the layer material and two variety of liquids (a) immersion oil (IO) and (b) di‐iodomethane (DI) as refracting medium to construct the LDP sensor. Optical ray tracing simulation is performed to optimize the sensor. The pressure sensor shows sensitivity as high as ±28.5 mV per 50 Pa pressure with an error ± 2.5 mV and repeatability of ~99.56% at full scale. We have shown the applicability of the sensor by capturing and analyzing respiratory pressure signals of some human subjects at numerous conditions.

中文翻译：

片上光流低压监测装置

我们提出了一种基于片上光流体表面可变形液鸽棱镜（LDP）的低流体流动压力监测装置。该设备的独特设计结合了液体和软固体，并通过光的全内反射实现了该传感器的高度灵敏性，并与微流体和/或芯片实验室设备的集成兼容。利用分层软光刻（LSL）和3D打印技术来制造该设备。我们已经使用聚二甲基硅氧烷（PDMS）作为层材料以及两种液体（a）浸油（IO）和（b）二碘甲烷（DI）作为折射介质来构造LDP传感器。进行光线追踪模拟以优化传感器。压力传感器的灵敏度每50 Pa高达±28.5 mV压力误差为±2.5 mV，满量程的可重复性约为99.56％。我们已经通过在许多条件下捕获和分析某些人类受试者的呼吸压力信号来表明该传感器的适用性。

更新日期：2020-11-10

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