Laser ionization mass spectrometry (LIMS) was one of the first practical methods developed for in situ analysis of the surfaces of solid samples. This review will encompass several aspects related to this analytical method. First, we will discuss the process of laser ionization, the influence of the laser type on its performance, and imaging capabilities of this method. In the second chapter, we will follow the historic development of LIMS instrumentation. After a brief overview of the first-generation instruments developed in 1960–1990 years, we will discuss in detail more recent designs, which appeared during the last 2–3 decades. In the last part of our review, we will cover the recent applications of LIMS for surface analysis. These applications include various types of analyses of solid inorganic, organic, and heterogeneous samples, often in combination with depth profiling and imaging capability.

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55 岁时的激光电离质谱：QUO VADIS？

激光电离质谱 (LIMS) 是最早开发的用于对固体样品表面进行原位分析的实用方法之一。本综述将涵盖与该分析方法相关的几个方面。首先，我们将讨论激光电离的过程、激光类型对其性能的影响以及该方法的成像能力。在第二章，我们将跟随LIMS仪器的历史发展。在对 1960-1990 年间开发的第一代仪器进行简要概述后，我们将详细讨论最近 2-3 年间出现的设计。在我们评论的最后一部分，我们将介绍 LIMS 在表面分析中的最新应用。这些应用包括固体无机、有机和异质样品的各种类型的分析，