Adaptive memory requires the organism to form associations that bridge between events separated in time. Many studies show interactions between hippocampus (HPC) and prefrontal cortex (PFC) during formation of such associations. We analyze neural recording from monkey HPC and PFC during a memory task that requires the monkey to associate stimuli separated by about a second in time. After the first stimulus was presented, large numbers of units in both HPC and PFC fired in sequence. Many units fired only when a particular stimulus was presented at a particular time in the past. These results indicate that both HPC and PFC maintain a temporal record of events that could be used to form associations across time. This temporal record of the past is a key component of the temporal coding hypothesis, a hypothesis in psychology that memory not only encodes what happened, but when it happened.

中文翻译：

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在联想记忆任务期间猴子海马和外侧前额叶皮层中什么和什么时候的联合表示

适应性记忆要求有机体在时间上分开的事件之间形成联系。许多研究表明，在形成这种关联的过程中，海马体 (HPC) 和前额叶皮层 (PFC) 之间存在相互作用。我们在记忆任务期间分析了来自猴子 HPC 和 PFC 的神经记录，该任务要求猴子将相隔约一秒的刺激联系起来。在第一个刺激出现后，HPC 和 PFC 中的大量单元依次启动。许多单位仅在过去特定时间出现特定刺激时才会触发。这些结果表明 HPC 和 PFC 都保留了可用于跨时间形成关联的事件的时间记录。过去的时间记录是时间编码假设的关键组成部分，