Front Cover: Kinetics of Drug Release via Nicardipine Hydrochloride‐loaded Carboxymethyl Cellulose/Poly(D,L‐lactic‐co‐glycolic acid) Nanocarriers Using a Contemporary Emulsion Process (ChemNanoMat 12/2020),ChemNanoMat

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Front Cover: Kinetics of Drug Release via Nicardipine Hydrochloride‐loaded Carboxymethyl Cellulose/Poly(D,L‐lactic‐co‐glycolic acid) Nanocarriers Using a Contemporary Emulsion Process (ChemNanoMat 12/2020)
ChemNanoMat ( IF 2.6 ) Pub Date : 2020-11-11 , DOI: 10.1002/cnma.202000567
Nopparuj Soomherun ₁ , Narumol Kreua‐ongarjnukool ₁ , Saowapa Thumsing Niyomthai ₁ , Sorayouth Chumnanvej ₂

Affiliation

Nicardipine hydrochloride‐loaded carboxymethyl cellulose/poly(D,L‐lactic‐co‐glycolic acid) nanocarriers were synthesized using a contemporary double emulsion process. The NCH‐CMC/PLGA nanocarriers can prolong the drug concentration and protect the drug from hydrolysis throughout a period of 16 days. The drug release kinetics indicated that the model followed the Korsmeyer‐peppas equation, leading to a combination of drug diffusion and polymer erosion. These nanocarriers could be an effective drug‐delivery agent for calcium channel blockers. More information can be found in the Full Paper by Narumol Kreua‐ongarjnukool, Sorayouth Chumnanvej et al.

中文翻译：

封面：使用现代乳化工艺通过载有盐酸尼卡地平的羧甲基纤维素/聚（D，L-乳酸-乙醇酸）纳米载体的药物释放动力学（ChemNanoMat 12/2020）

盐酸尼卡地平加载的羧甲基纤维素/聚（d，L-乳酸-共-glycolic酸）纳米载体使用当代双乳液方法合成。NCH-CMC / PLGA纳米载体可在16天的时间内延长药物浓度并保护药物免受水解。药物释放动力学表明该模型遵循Korsmeyer-peppas方程，从而导致药物扩散和聚合物侵蚀。这些纳米载体可能是钙通道阻滞剂的有效药物递送剂。有关更多信息，请参见Sorayouth Chumnanvej等人的Narumol Kreua-ongarjnukool撰写的全文。

更新日期：2020-12-07

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