We applied our lab-built CO₂ laser photoacoustic spectrometer, which has a multi-component measurement capability, for measuring the ammonia, acetone, and ethylene trace gases in the breath of 10 renal disease patients and 30 healthy volunteers. We argue that not only ammonia but also acetone and ethylene can become potential biomarkers for renal disease. We found that the breath ammonia and acetone concentrations from the renal disease patients are significantly higher than that of the healthy volunteers. While for ethylene, we found that the breath ethylene concentration from renal disease patients is not significantly higher than in the healthy volunteer. Besides a reconfirmation of the breath ammonia concentration as a biomarker for renal disease, our results open up a possibility for the breath acetone to be a possible biomarker for renal disease.

我们应用了实验室制造的CO ₂激光光声光谱仪具有多组分测量功能，可测量10名肾病患者和30名健康志愿者的呼吸中的氨，丙酮和乙烯微量气体。我们认为，不仅氨而且丙酮和乙烯都可能成为肾脏疾病的潜在生物标志物。我们发现，肾脏疾病患者的呼吸氨和丙酮浓度显着高于健康志愿者。对于乙烯，我们发现来自肾脏疾病患者的呼吸乙烯浓度没有显着高于健康志愿者。除了再次确认呼气中的氨气浓度是肾脏疾病的生物标志物外，我们的研究结果还为呼气丙酮成为肾脏疾病的生物标志物提供了可能性。